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Sjogren’s Syndrome Presenting as Hypokalemic Paralysis Secondary to Distal Renal Tubular Acidosis: A Case Report

Year: 2024

Type: article

Abstract: Sjogren's syndrome (SS) is an autoimmune disease affecting multiple exocrine glands such as salivary and lacrimal glands, with focal lymphocytic infiltration. The disease predominantly affects women. The classic presentation is xerostomia and keratoconjunctivitis. In adult populations, tubulointerstitial nephritis, which can manifest as renal tubular acidosis (RTA), is the most prevalent renal manifestation of SS. However, in pediatric populations, RTA only occurs in 7.1-19.2% of cases with renal potassium wasting or hypokalemic paralysis. Here, we describe a case of SS manifesting with hypokalemic paralysis with underlying distal renal tubular acidosis (dRTA).

Source: Cureus

DOI: 10.7759/cureus.72488

Authors: Ashwath Ravisankar, Varshini Thiruvadi, Souwdamini Sethuram, Naveen Prasad Gopalakrishnan Ravikumar

Institutions: Apollo Hospitals, OSF Saint Francis Medical Center, Apollo Hospitals

Language: English

Topic: Salivary Gland Disorders and Functions

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4403799037