Year: 2024
Type: article
Abstract: Statins, as hydroxymethylglutaryl coenzyme A reductase inhibitors, have a significant effect on lowering cholesterol, and are widely used in the clinical treatment of cardiovascular and cerebrovascular diseases, and are potent drugs for the prevention and treatment of coronary heart disease. Recent studies have shown that statins also have other effects, such as lowering blood pressure, lowering blood glucose, stabilizing atherosclerotic plaques, slowing down the proliferation and migration of smooth muscle cells, anti-inflammatory and antihypertensive, etc., which are very significant. This paper addresses the physicochemical properties, pharmacological effects, adverse effects, and therapeutic applications of statins in the treatment of cardiovascular diseases (coronary heart disease).
Authors: Junshu Wang, Xinyue Feng, Haoyang Tan
Institution: Soochow University
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4403806801