Work

Refractory Kawasaki Disease With a Giant Aneurysm Successfully Treated With Infliximab and Enoxaparin: A Case Report

Year: 2024

Type: article

Abstract: Kawasaki disease (KD) is the most common vasculitis in children, and can result in the development of coronary artery aneurysms (CAAs) if not properly managed. While intravenous immunoglobulin (IVIG) and aspirin are standard first-line treatments, refractory KD may develop, increasing the risk of coronary complications. Herein, we report the case of a young girl with KD who initially responded to IVIG, but later developed a giant CAA, despite additional treatments. Infliximab stabilized her condition, and one year later, the CAA remained stable without thrombus formation. This case demonstrates that clinical appearance, particularly fever, may not fully reflect the patient's condition, as fever can subside immediately after treatment, but may relapse days later, underscoring the need for vigilant monitoring.

Source: Journal of Pediatric Health Care

DOI: 10.1016/j.pedhc.2024.09.001

Authors: Zhe-Jia Liu, Wan-Fu Hsu

Institutions: Tri-Service General Hospital, National Defense Medical Center

Language: English

Topic: Kawasaki Disease and Coronary Complications

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $2,550