Work

A New Platform Molecule from Gluconolactone? Access to Furanics, Rare Sugars, β‐Ketoamides and Amino Furanones

Year: 2024

Type: article

Abstract: Gluconolactone serves as a readily available and inexpensive starting material for synthesizing the potential platform chemical (Z)-3-deoxy-1,2 : 5,6-di-O-isopropylidene-D-erythro-hex-3-enolactone in two steps. In this work, the selective elimination of triacetone gluconolactone was optimized. The resulting product is a versatile molecule, capable of being transformed into various compound classes in one or a few steps, i. e. potentially a new biomass-based platform chemical. This study demonstrates how it can be transformed into furanics, rare sugars, β-ketoamides, and amino furanones.

Source: Chemistry - A European Journal

DOI: 10.1002/chem.202403453

Authors: Arminas Jurys, Christian Marcus Pedersen

Institution: University of Copenhagen

Language: English

Topic: Catalysis for Biomass Conversion

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $4,640

Funders: Novo Nordisk, Danmarks Frie Forskningsfond, Novo Nordisk Fonden