Work

Non-surgical management of methicillin-sensitive Staphylococcus aureus bacteremia-related mediastinitis

Year: 2024

Type: article

Abstract: Background: . Case presentation: In a 79-year-old man judged not eligible for cardiac surgery, we attempted the infection source control through vacuum-assisted closure therapy, together with antimicrobial therapy. We observed gradual clinical, laboratory and radiologic improvements: reduced swelling and normalization of the white blood cell count and C-reactive protein level were associated with reduction in size of a periaortic abscess. Conclusion: We managed a clinical condition with high mortality risk with chronic antimicrobial therapy alone, a strategy that is rarely considered. With this medical strategy we achieved an optimal response to a clinical picture that does not allow any other approach. LEARNING POINTS: Mediastinitis is a rare but severe infection with a high mortality rate.Chronic antimicrobial therapy can be an effective strategy in high surgical risk patients.The present case demonstrates good tolerability of lifelong antibiotic therapy.

Source: European Journal of Case Reports in Internal Medicine

DOI: 10.12890/2024_004899

Authors: Carlo Vignati, Alessandra Pietragalla, Gianfranco Dedivitiis, Maria Elisabetta Mancini, Piergiuseppe Agostoni

Institutions: University of Milan, Centro Cardiologico Monzino, Luigi Sacco Hospital, ASST Fatebenefratelli Sacco

Language: English

Topic: Infectious Aortic and Vascular Conditions

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $323