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Drug-Induced Delirium Associated With Sacubitril/Valsartan in a Patient With Chronic Kidney Disease: A Case Report

Year: 2024

Type: article

Abstract: Drug-induced neuropsychiatric symptoms are not uncommon, particularly in patients with multiple comorbidities and polypharmacy. Sacubitril/valsartan is a combination medication used in the treatment of heart failure, especially for reducing hospitalizations in patients with heart failure with preserved ejection fraction (HFpEF). However, its neurological side effects, including delirium, hallucinations, and confusion, have been increasingly reported. This case report explores the occurrence of drug-induced delirium, specifically visual hallucinations, in a 79-year-old male with HFpEF and end-stage kidney disease (ESKD) after starting sacubitril/valsartan.

Source: Cureus

DOI: 10.7759/cureus.72524

Authors: Oscar Y Pena, Kim Kyung

Institutions: Quinnipiac University, St. Vincent's Medical Center

Language: English

Topic: Intensive Care Unit Cognitive Disorders

Subfield: Critical Care and Intensive Care Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4403841618