Year: 2024
Type: conference-paper
Abstract: This research paper presents a novel approach to predicting drug-drug interactions (DDIs) through the integration of computational methodologies and pharmaceutical expertise. The accurate anticipation of potential interactions between medications is crucial for ensuring patient safety and optimizing therapeutic outcomes in an era marked by a growing array of medications and increasing complexities in drug therapy regimens. Drawing inspiration from the pressing need within the pharmaceutical industry and healthcare sector, this research aims to develop reliable predictive models capable of identifying and mitigating the risks associated with DDIs. Leveraging diverse data sources and cutting-edge machine learning techniques, our methodology encompasses matrix perturbation, similarity-based modeling, and ensemble learning algorithms, each offering unique insights into the underlying mechanisms driving drug interactions. Evaluation metrics including accuracy, F1 Score, and recall are utilized to assess the performance of our model, with visualization techniques providing insights into the dynamics of drug interaction networks. Through comprehensive experimentation and analysis, our findings contribute to advancing drug safety and therapeutic decision-making, ultimately benefiting patient care and public health on a global scale.
Authors: Drishika Chauhan, Navjyot Narang, Pratyasha Shukla, Kirti Aggarwal
Institution: Jaypee Institute of Information Technology
Language: English
Subfield: Computational Theory and Mathematics
Field: Computer Science
Domain: Physical Sciences
Open Access status: gold
OpenAlex ID: W4403854093