The role of colchicine on ventricular remodelling following myocardial infarction and ischemia-reperfusion injury: article review
Year: 2024
Type: article
Abstract: Acute myocardial infarction (AMI) is a major cause of cardiac dysfunction, arrhythmias, and a poor prognosis. Even though new technologies have been developed to aid in opening the culprit coronary artery and correcting ischemia-related stenosis by percutaneous coronary intervention (PCI), the ventricular remodelling that induces cardiac failure as a consequence of AMI remains unchanged. Colchicine, a versatile anti-inflammatory medication, has been documented in mitigating cardiac remodelling and enhancing cardiac function following AMI. This article provides an in-depth review of the processes by which colchicine affects ventricular remodeling after AMI, highlighting the potential role of inflammation in the pathogenesis and progression of ventricular dysfunction. Keyword: Colchicine, Ischemia-Reperfusion Injury, Myocardial Infarction, Ventricular Remodelling
Source: Heart Science Journal
Authors: Fahreza Caesario, Indra Prasetya
Institution: University of Brawijaya
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4403862620