Figure 1 from A Database Tool Integrating Genomic and Pharmacologic Data from Adrenocortical Carcinoma Cell Lines, PDX, and Patient Samples
Year: 2024
Type: other
Abstract: Overview of the datasets and reproducibility of ACC CellMiner. A, URL and snapshot of the website for ACC_CellMinerCDB. B, Summary of the molecular and drug activity data for cell lines, patient-derived mouse xenografts, and surgical samples included in ACC CellMiner. For each type of molecular and drug data, numbers indicate how many genes or drugs are included. Gray boxes indicate items with no data. C, Table of samples overlapping between datasets (top) and cell lines included in each dataset (bottom). D, Distribution of gene expression correlation between “ACC NCI plus surgical” and “ACC Colorado plus PDX” data sets. E, CTNNB1, IGF2, and NR5A1 gene expressions in the two data sets are plotted, and Pearson’s correlation coefficients are shown at the top of the plots. *Only the TVBF-7 cell line has methylation data.
Authors: Yasuhiro Arakawa, Fathi Elloumi, Sudhir Varma, Prashant Khandagale, Ukhyun Jo, Suresh Kumar, Nitin Roper, William C. Reinhold, Robert W. Robey, Naoko Takebe, Michael M. Gottesman, Craig J. Thomas, Valentina Boeva, Alfredo Berruti, Andrea Abate, Mariangela Tamburello, Sandra Sigala, Constanze Hantel, Isabel Weigand, Margaret E. Wierman, Katja Kiseljak-Vassiliades, Jaydira Del Rivero, Yves Pommier
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4403887091