Figure 2 from A Database Tool Integrating Genomic and Pharmacologic Data from Adrenocortical Carcinoma Cell Lines, PDX, and Patient Samples
Year: 2024
Type: other
Abstract: RNA-seq (xsq) expression of hormonal and drug efflux genes in the ACC cell lines and surgical samples. A, Univariate analysis scatterplot of the hormonal genes SULT2A1 (sulfotransferase family 1A member 1) vs. CYP11A1 (cytochrome P450 family 11 subfamily A member 1) transcript levels in ACC NCI cell lines and surgical samples. Transcript levels of the two genes in the 1,011 cell lines in the CCLE dataset were merged. B, Univariate analysis scatterplot of the drug transporters ABCB1 (MDR1) vs. ABCG2 (BCRP) transcript expression levels in ACC NCI cell lines and surgical samples. Transcriptional expression levels of ABCB1 and ABCG2 in the 1,011 cell lines of the CCLE dataset were merged with the ACC data.
Authors: Yasuhiro Arakawa, Fathi Elloumi, Sudhir Varma, Prashant Khandagale, Ukhyun Jo, Suresh Kumar, Nitin Roper, William C. Reinhold, Robert W. Robey, Naoko Takebe, Michael M. Gottesman, Craig J. Thomas, Valentina Boeva, Alfredo Berruti, Andrea Abate, Mariangela Tamburello, Sandra Sigala, Constanze Hantel, Isabel Weigand, Margaret E. Wierman, Katja Kiseljak-Vassiliades, Jaydira Del Rivero, Yves Pommier
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4403887092