Work

Angiotensin II administration in severe thrombocytopenia and chronic venous thrombosis: A case report

Year: 2024

Type: article

Abstract: BACKGROUND: The initial trials on angiotensin II (AT II) administration indicated a high incidence of thrombocytopenia and thrombosis, as well as a positive correlation between hyperreninemia and response to the medication. CASE SUMMARY: We describe a case of a patient presenting with catecholamine resistant septic shock, thrombocytopenia, deep vein thrombosis, and normal renin concentration who responded immediately to AT II treatment. We observed no worsening of thrombocytopenia and no progression of thrombosis or additional thromboses during treatment. CONCLUSION: Our case underscores the need for individualized assessment of patients for potential therapy with AT II.

Source: World Journal of Critical Care Medicine

DOI: 10.5492/wjccm.v13.i4.96755

Authors: Ana Vujaklija Brajkovic, Andrej Markota, Luka Bielen, Andro Vujević, Mia Rora, Radovan Radonic

Institutions: University Hospital Centre Zagreb, University of Zagreb, University Clinical Centre Maribor

Language: English

Topic: Renin-Angiotensin System Studies

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4403903725