Differential expression of ORAI channels and STIM proteins in renal cell carcinoma subtypes: implications for metastasis and therapeutic targeting
Year: 2024
Type: article
Abstract: regulating focal adhesion kinase (FAK) and Cyclin D1 in both cell lines. These findings highlight the critical roles of Orai1 and Orai3 in RCC metastasis, with Orai3 linked to poorer prognosis in females with pRCC. This study offers valuable insights into RCC diagnostics and potential therapeutic strategies targeting ORAI channels and STIM proteins.
DOI: 10.4196/kjpp.24.126
Authors: Ji-Hee Kim, Kyu-Hee Hwang, Jiyeon Oh, Sung-Eun Kim, Mi-Young Lee, Tae Sic Lee, Seung-Kuy Cha
Institutions: Soonchunhyang University, Yonsei University
Language: English
Topic: Ion Channels and Receptors
Subfield: Sensory Systems
Field: Neuroscience
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W4403929439