Work

Immune Thrombocytopenic Purpura (ITP) With Ulcerative Colitis (UC)

Year: 2024

Type: article

Abstract: Inflammatory bowel disease (IBD) includes ulcerative colitis (UC) and Crohn's disease. A relapsing, immune-modulated illness, it causes inflammation of the small and large intestines. UC is sometimes associated with extra-intestinal manifestations, including autoimmune cytopenias. Immune thrombocytopenic purpura (ITP) is a rare disorder which may induce an antibody-mediated, isolated reduction in platelet counts. ITP can present with extra-intestinal manifestations; the diagnosis follows the exclusion of other etiologies. Co-occurrences of ITP and UC in patients commonly are at the onset of UC or during illness recurrences. The severity of ITP correlates with the degree of UC pathology. We present a unique case of a 70-year-old presenting ulcerative colitis with immune thrombocytopenic purpura.

Source: Cureus

DOI: 10.7759/cureus.72778

Authors: Sohaib K Mohammed, Sanjana Budamagunta, Waleed A Khan, Muneeb Khan, Steven Lippmann

Institutions: Countess of Chester Hospital NHS Foundation Trust, Countess of Chester Hospital, Deccan College of Medical Sciences, University of Louisville

Language: English

Topic: Platelet Disorders and Treatments

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4403938737