Work

Myosin-binding protein-H: Not just filler

Year: 2024

Type: article

Abstract: Decades of research into striated muscle have provided a robust understanding of the structure and function of the sarcomere and its protein constituents. However, a handful of sarcomere proteins remain that have had little to no functional characterization. These are typically proteins that are highly muscle-type specific or are products of alternative start sites or alternative splicing.

Source: The Journal of General Physiology

DOI: 10.1085/jgp.202413622

Author: David Y. Barefield

Institution: Loyola University Chicago

Language: English

Topic: Cardiomyopathy and Myosin Studies

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

Open Access status: hybrid

Funders: National Institutes of Health, National Heart, Lung, and Blood Institute

Awards: Myofilament proteins in cardiomyopathy and arrhythmias, Regulation of atrial contractility in cardiomyopathy