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Infectious Morbidity and All-cause Mortality of Infants HIV-exposed Uninfected Compared to Infants HIV-unexposed Uninfected in Botswana

Year: 2024

Type: article

Abstract: Some studies have reported increased infectious morbidity and all-cause mortality risk among infants HIV-exposed uninfected compared with infants HIV-unexposed uninfected. In a retrospective analysis of infants enrolled in the Botswana-based Tshilo Dikotla study, we found no difference in the prevalence of infectious hospitalizations or deaths from any cause in the first year of life by perinatal HIV exposure.

Source: The Pediatric Infectious Disease Journal

DOI: 10.1097/inf.0000000000004603

Authors: Melanie M. Dubois, Jennifer Jao, Shan Sun, Justine Legbedze, Sara Schenkel, Nicholas Mmasa, Samuel W. Kgole, Gosego Masasa, Anna-Ursula Happel, Saori C. Iwase, Roxanna Haghighat, Sikhulile Moyo, Tanvi S. Sharma, Paul T. Edlefsen, Danica Shao, Heather Jaspan, Kathleen M. Powis

Institutions: Boston Children's Hospital, Harvard University, Massachusetts General Hospital, Weill Cornell Medicine, Mass General Brigham, Northwestern University, Lurie Children's Hospital, County Durham and Darlington NHS Foundation Trust, Darlington Memorial Hospital, University of Cape Town, Institute of Infectious Disease and Molecular Medicine, University of Botswana, Stellenbosch University, University of Pretoria, Fred Hutch Cancer Center, University of Washington, Seattle Children's Research Institute

Language: English

Topic: HIV/AIDS Research and Interventions

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Institute of Allergy and Infectious Diseases, National Institute of Diabetes and Digestive and Kidney Diseases

Awards: G2684019295, G8782086962, Program for AIDS Clinical Research Training (PACRT), G90079629, G966175068

OpenAlex ID: W4403970448

FWCI: 1.261

Cites: 9

Cited by: 4

Related to: 10