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Tumor‐derived lactic acid promotes acetylation of histone H3K27 and differentiation of IL ‐10‐producing regulatory B cells through direct and indirect signaling pathways

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Year: 2024
Type: article
Source: International Journal of Cancer
DOI: 10.1002/ijc.35229
Authors: Satoshi Muraoka, Takashi Baba, Takashi Akazawa, Kei‐ichi Katayama, Hiroki Kusumoto, Shimpei Yamashita, Yasuo Kohjimoto, Sadahiro Iwabuchi, Shinichi Hashimoto, Isao Hara, Norimitsu Inoue
Institutions: Wakayama Medical University, Wakayama University, Osaka International Cancer Institute
Language: English

Topic: T-cell and B-cell Immunology
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funder: Japan Society for the Promotion of Science
Awards: 腫瘍随伴マクロファージの多様な乳酸シグナルネットワークの解明, Development of breakthrough therapies against hyper lactic acid signaling in cancer immune microenvironment, The signaling mechanism of immune mediator lactic acid secreted from cancer, Lactic acid signaling in the renal cancer microenvironment.
OpenAlex ID: W4403990353
FWCI: 1.905
Cites: 48
Cited by: 14
Related to: 10
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