Uterine fibroid metastasis as the initial manifestation of lobular breast cancer
Year: 2024
Type: article
Study design: Case Report
Abstract: The occurrence of breast cancer metastasis in a uterine leiomyoma is exceptional, and its diagnosis prior to detection of the primary tumor is even rarer. We describe at case of a 52-year-old female patient with a large fast growing uterine fibroid that caused pelvic pain and abdominal distention. A total abdominal hysterectomy with bilateral salpingo-oophorectomy was performed. Histopathology of the surgical specimen showed a characteristic pattern of invasive breast lobular carcinoma in the leiomyoma. A magnetic resonance image of the breast was then performed, which reveled primary and bilateral breast cancer. She subsequently underwent neoadjuvant endocrine therapy plus cyclin inhibitors, breast-conserving surgery, and radiotherapy. To date, the patient is alive and asymptomatic after 3 years of follow-up.
Authors: Castilla Rodríguez M MD, García Tejedor A MDPHD, Martínez García JM MD, Ortega Expósito C MD, Campos Delgado M MD, Guevara Peralta R MD, Alemany Carro J MD, Odon Cañizares A MD, Pla Farnós MJ MDPHD, Ponce y Sebastiá J MDPHD
Language: English
Subfield: Pathology and Forensic Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4404007545