The Biochemistry and Clinical Significance of D-Dimer
Year: 2024
Type: article
Abstract: D-dimer, product degradation of fibrin, belongs to the most sensitive and specific markers in the diagnostics of thrombotic disorders, mainly acute PE and DVT. This leads to its measurement because of the high sensitivity in ruling out these conditions, thus reducing unnecessary imaging and improving patient management. The importance of D-dimer has been repeatedly said in various studies, notably during the COVID-19 pandemic, where it has been noted as an essential biomarker in the assessment of thrombotic complications, treatment strategy, and prognostic aspects of the patient. This literature review paper covers basic principles and measurements of D-dimer because of up-to-date knowledge on its clinical applications, limitations, and directions for potential future research.
Author: Umalbaneen Hussain Ismael
Language: English
Subfield: Internal Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W4404018758