Work

From burst to controlled release: using hydrogel crosslinking chemistry to tune release of micro-crystalline active pharmaceutical ingredients

Year: 2024

Type: article

Abstract: In this study, a nanoemulsion of a BCS class II drug, fenofibrate, was cross-linked via a Michael-type addition reaction to yield micro-crystalline Fen-embedded micro-hydrogels with tunable degradation.

Source: RSC Pharmaceutics

DOI: 10.1039/d4pm00186a

Authors: Purnima N. Manghnani, Arif Z. Nelson, Kelvin Wong, Yi Wei Lee, Saif A. Khan, Patrick S. Doyle

Institutions: Singapore-MIT Alliance for Research and Technology, National University of Singapore, Harvard University, Massachusetts Institute of Technology

Language: English

Topic: Hydrogels: synthesis, properties, applications

Subfield: Molecular Medicine

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4404026985

FWCI: 1.504

Cites: 29

Cited by: 14

Related to: 10