Work

An adverse outcome pathway approach linking retinoid signaling disruption to teratogenicity and population-level outcomes

Year: 2024

Type: article

Abstract: of 1 - 1.21 µg/L across the same exposure windows. ATRA exposure (1 µg/L) resulted in 50 % food ingestion inhibition at 7 days post fertilization (dpf) and 10 % survival at 14 dpf. This study provides a regulatory-relevant framework linking developmental effects to population outcomes, highlighting ecological risks and needs for improved risk assessments.

Source: Aquatic Toxicology

DOI: 10.1016/j.aquatox.2024.107143

Authors: Audrey Phan, Aleksandra Sokolova, Klara Hilscherova

Institutions: Masaryk University, RECETOX

Language: English

Topic: Environmental Toxicology and Ecotoxicology

Subfield: Health, Toxicology and Mutagenesis

Field: Environmental Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,460