Work

Primary Pulmonary Choriocarcinoma With Lymph Node Metastasis: A Case Report and Brief Review

Year: 2024

Type: article

Abstract: Choriocarcinoma is a malignant germ cell tumor containing syncytiotrophoblasts and secreting human chorionic gonadotropin (β-hCG), often associated with a poor prognosis. Reports of primary choriocarcinoma of the lung with lymph node metastasis are extremely rare in the literature. Here, we report a surgically treated case of primary pulmonary choriocarcinoma in a 32-year-old woman. Surgery was followed by three cycles of chemotherapy with etoposide, methotrexate, actinomycin D, leucovorin calcium, cyclophosphamide, and vincristine. Her post-treatment PET scan showed no evidence of disease, and her β-hCG remains at nadir level. She is currently on monthly hCG surveillance and is in good condition.

Source: Cureus

DOI: 10.7759/cureus.73010

Authors: Chinedu Okoli, Brianna Philbrick, Syed Quadri

Institutions: Maine Medical Center, MaineHealth, Maine Medical Center

Language: English

Topic: Gestational Trophoblastic Disease Studies

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4404027450