Work

Persistent Visual Field Deficit After Half-fluence Photodynamic Therapy for Chronic Central Serous Chorioretinopathy

Year: 2024

Type: article

Abstract: PURPOSE: To report a rare case of a persistent paracentral scotoma after half-fluence photodynamic therapy for chronic central serous chorioretinopathy. METHODS: A 65-year-old man with a history of chronic central serous chorioretinopathy presented with a temporal paracentral visual distortion 1 week after undergoing repeat off-label treatment with half-fluence verteporfin photodynamic therapy for recurrent intraretinal fluid exudation in the right eye. Fundus photography, fundus autofluorescence, optical coherence tomography, fluorescein angiography, indocyanine green angiography, and automatic visual field testing were obtained. RESULTS: Humphrey visual field 10-2 demonstrated a focal temporal paracentral area of reduced sensitivity, which remained persistent on repeat testing up to 9 months. Optical coherence tomography macula and fluorescein angiography demonstrated subtle corresponding changes in the nasal macula, while indocyanine green angiography demonstrated no visible alteration in choroidal perfusion. CONCLUSION: Symptomatic scotoma in the location of laser treatment may be a rare complication of verteporfin photodynamic therapy even at reduced fluence, in the setting of repeat treatment in the same location, and may be identified and monitored with automated 10-2 visual field testing.

Source: Retinal Cases & Brief Reports

DOI: 10.1097/icb.0000000000001683

Authors: Paul S. Micevych, Jay M. Stewart

Institution: University of California, San Francisco

Language: English

Topic: Retinal Diseases and Treatments

Subfield: Ophthalmology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funder: Research to Prevent Blindness