Local Refractive Index Sensitivity of Localized Surface Plasmon Resonance Biosensors
Year: 2024
Type: article
Abstract: High Resolution Image Download MS PowerPoint Slide The sensitivity of localized surface plasmon resonance (LSPR) biosensors to a change in the local refractive index (RI) is investigated theoretically. By combining an effective medium theory and a quasistatic theory, analytical expressions for the local RI sensitivity are derived. Electromagnetic simulations show that the expressions can predict the sensitivity well for LSPR biosensors of various sizes and geometries including nanocylinders, nanodisks, nanorods and nanotriangles for both two- and three-layer systems. Like the bulk RI sensitivity, the local RI sensitivity is shown to depend linearly on the resonant wavelength of the biosensors. Other than two parameters used to linearize the dielectric function of the metal core, there are no fitting parameters. Hence, the expressions can be used to predict the local RI sensitivity of LSPR biosensors directly from the resonant wavelength.
Authors: Allison Rabbani, Rachel Rudacille, Keisuke Hasegawa
Institution: Grinnell College
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: hybrid
Estimated APC paid: $4,500
Funder: Grinnell College
OpenAlex ID: W4404032717
