Work

The state of lipid metabolism in patients with diabetic nephropathy

Year: 2024

Type: article

Abstract: Aim This study aimed to evaluate the state of lipid metabolism in patients with diabetic nephropathy . Methods In this open label, randomised, prospective study. The study included 120 patients with type 2 diabetes , whose average age was 58.79 ± 1.27 years. In general, the average diabetes experience was 7 ± 3.16 years, HbA1C-9.3 ± 1.82 %, BMI-28.05 ± 3.45. Non-HDL cholesterol levels were calculated (non-HDL cholesterol = total cholesterol - HDL). Results As a result of the analysis, a negative relationship of moderate strength was revealed between eGFRcr levels in the blood of TCh ( r = -0.32; p < 0.01), triglycerides ( r = -0.51; p < 0.018), non-HDL ( r = –0.44; p < 0.01) and weak positive association with HDL ( r = 0.28; p = 0.01). Negative relationships were also established between the A/Cr index and the blood level of TCh ( r = -0.37; p < 0.01), triglycerides ( r = –0.42; p < 0.01), non-HDL ( r = – 0.35; p < 0.01)/ Conclusion Therefore, in patients with type 2 diabetes, it is advisable to determine the level of TG in the blood even with reference or slightly elevated levels of TG and non-HDL to predict DN.

Source: Archives of Gerontology and Geriatrics Plus

DOI: 10.1016/j.aggp.2024.100095

Authors: Lola Daminova, Sitorakhon Muminova, Bakhodir Nigmonov

Institutions: Tashkent State University of Law, Tashkent Pediatric Medical Institute

Language: English

Topic: Chronic Kidney Disease and Diabetes

Subfield: Nephrology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,100