Work

Chemical composition and pharmacological aspects of Malaysian stingless bee propolis: An up‑to‑date systematic review

Year: 2024

Type: review

Abstract: Propolis is a sticky substance produced by stingless bees for construction and defence of their hive. It has notable anti‑inflammatory, antioxidant, antibacterial, antifungal, anti‑hyperglycemic, and wound healing effects. The present review summarised and examined the phytochemical properties, mode of action and current research prospects of Malaysian propolis. A database search using Google Scholar, Web of Science and ScienceDirect generated 780 references; 30 relevant articles were included in the present review, of which 23 were in vitro studies and 7 were in vivo or animal studies. Propolis demonstrated antioxidant, antibacterial, antifungal, anti‑inflammatory and anti‑hyperglycemic properties, indicating potential as a wound healing agent. Despite favourable findings, due to the scarcity of studies in the literature, more in‑depth research and clinical validation on the synergistic effects, efficacy and optimum dosage of propolis are needed.

Source: Biomedical Reports

DOI: 10.3892/br.2024.1887

Authors: Nor Jusril, Khamsah Mohd, Nurliana Abd Mutalib, Ainur Mohd Badiazaman

Institutions: Sultan Zainal Abidin University, Universiti Teknologi MARA

Language: English

Topic: Bee Products Chemical Analysis

Subfield: Insect Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

Funder: Universiti Sultan Zainal Abidin