An electrochemiluminescence sensor for ultrasensitive determination of tyrosine based on ceria nanomaterial as a novel luminophor
Year: 2024
Type: article
Abstract: BACKGROUD: Recently, optical nanomaterials have attracted much attention in the field of electrochemiluminescence (ECL). Nanostructured ceria possessed unique optical properties, and it's always used for constructing ECL sensor as catalyst for improving sensing performance, while the ECL property of ceria is rarely studied. In fact, it could be the potential candidate for applying in ECL sensors based on size and shape dependency optical property caused by the quantum scale effects. Therefore, new simple and efficient ceria nanomaterial used as luminophor for constructing the ECL sensor have aroused more research interest and motivation. (91 words). RESULTS: -NC for Tyrosine (Tyr) determination owing to the electron transform between the luminous of ceria and Tyr resulting in the cathodic ECL intensity quenched correspondingly, and it has possessed excellent sensing performance with a linear range of 0.005-20 nmol/L and the limit of detection (LOD) value of 1.7 fmol/L (141 words) SIGNIFICANCE AND NOVELTY: The proposed method demonstrated excellent selectivity and ultra-sensitivity toward Tyr, which had been used for the determination of Tyr in human serum successfully, possessing outstanding analytical performance. Therefore, nanostructured ceria is a new category of efficient and promising luminophore, which would open new avenues for the potential application in the field of ECL sensing for clinical diagnosis. (57 words).
Source: Analytica Chimica Acta
Authors: Yaxuan Qian, Zhihua Wang
Institutions: Wuhan Business University, Northwest Normal University
Language: English
Subfield: Electrical and Electronic Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: hybrid
Estimated APC paid: $4,070
OpenAlex ID: W4404092886