Novel tools for evaluating COVID-19 at the emergency department: Surfactant protein D level and CHARISMA score
Year: 2024
Type: article
Study design: Observational Study
Abstract: Objectives: To investigate the serum surfactant protein D (SP-D) level required to determine the diagnosis and prognosis of coronavirus disease 2019 (COVID-19), and create a new scale for disease prognosis prediction. Methods: . Results: Serum SP-D levels differed significantly across the groups. There was a strong correlation between SP-D levels and infiltration volumes. CHARISMA scores were higher in the severe than in the mild ARDS group and in patients who died than in survivors. In the receiver operating characteristic curve analysis of the CHARISMA scores, a cutoff value of 4 indicated mortality. Conclusion: Serum SP-D levels can be used to determine COVID-19 diagnosis and prognosis, and the CHARISMA score can be used to predict prognosis and mortality risk in patients with COVID-19 pneumonia.
Source: Heliyon
Institution: Trakya University
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,100
OpenAlex ID: W4404093728