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Effects of urinary organophosphate flame retardants in susceptibility to attention-deficit/hyperactivity disorder in school-age children

Year: 2024
Type: article
Study design: Observational Study
Abstract: exposure scenarios, and urinary phthalate metabolites, parabens, bisphenol-A and creatinine, levels of urinary BDCPP, TDCPP, and TBEP in ADHD children showed significant and dose-dependent effects on core behavioral symptoms of inattention. DNBP levels were positively correlated with neuropsychological deficits (CPT detectability, omission, and commission), while urinary DPHP in ADHD children were negatively related to CPT detectability and commission. Hyperactivity and impulsivity were not correlated with urinary OPFRs and their metabolites in ADHD children. In conclusion, the ADHD symptom of inattention and CPT performance may be closely associated with certain urinary OPFRs and their metabolites, independent of urinary PAE metabolites, parabens, and bisphenol-A in school-age-ADHD children.
DOI: 10.1016/j.ecoenv.2024.117281
Authors: Liang-Jen Wang, How-Ran Chao, Chih-Cheng Chen, Ching-Me Chen, Huey-Ling You, Ching-Chang Tsai, Ching-Shu Tsai, Wen-Jiun Chou, Chia-Jung Li, Kai Fan Tsai, Fu-Jen Cheng, Chia-Te Kung, Shau-Hsuan Li, Chin-Chou Wang, Yu-Che Ou, Wen-Chin Lee, Wan-Ting Huang
Institutions: Chang Gung University, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung Medical University, National Pingtung University of Science and Technology, Cheng Shiu University, Fooyin University
Language: English
Open Access status: gold
Estimated APC paid: $2,990
OpenAlex ID: W4404099437
FWCI: 0.95
Cites: 66
Cited by: 6
Related to: 10