Effect of Intra-peritoneal Levo-bupivacaine on Post Laparoscopic Pain - a Triple Blinded Randomized Controlled Study
Year: 2024
Type: article
Study designs: Randomized Controlled Trial, Clinical Trial
Abstract: Laparoscopic cholecystectomy offers benets like reduced pain and faster recovery, but postoperative pain persists, mainly due to peritoneal irritation and CO2 effects. This study assessed intraperitoneal levobupivacaine's effectiveness in managing pain compared to 0.9% sodium chloride. In a randomized, triple-blinded, placebo-controlled study, 118 women undergoing diagnostic laparoscopic surgery were divided into two groups: Group 1 received 0.25% levobupivacaine, while Group 2 received 0.9% sodium chloride. Pain levels were assessed at 0, 12, 24, and 48 hours postoperatively using the visual analogue scale. The results indicated that Group 1 experienced signicantly lower pain levels at all time points (p < 0.05) and required less analgesia than Group 2. Moreover, Group 1 reported higher satisfaction with postoperative management. The study concluded that intraperitoneal levobupivacaine provides superior pain relief, reduces the need for additional analgesics, and enhances patient satisfaction compared to sodium chloride, making it a more effective strategy for postoperative pain management following laparoscopic surgery
Authors: Kotla Nikitha, Pragya Mishra
Institution: M.J.P. Rohilkhand University
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4404108663