A Comparative Study to Evaluate the Therapeutic Efficacy and Safety of Autoinoculation of Capsule Versus Whole Lesion of Molluscum Contagiosum
Year: 2024
Type: article
Abstract: Background: Molluscum contagiosum is caused by molluscum contagiosum virus (MCV) of poxviridae family. Several treatment options are ablative, topical agents or immunomodulatory therapy. Autoinoculation helps in inducing a cell-mediated immune response to the antigens, aiding clearance of lesions. To Objective: assess the comparative therapeutic efcacy and safety of technique for Autoinoculation of capsule versus Autoinoculation of whole lesion of molluscum contagiosum. Molluscum contagiosum cases having minimum 5 lesions and age Methods: between 5 to 60 years were taken in this study. Out of total 50 patients, 25 patients (group A) treated with autoinoculation of capsule of molluscum lesion (i.e. the covering of lesion of molluscum after evisceration or enucleation of whitish core of Mollusca) and the other 25 patients (group B) treated with autoinoculation of whole lesion of molluscum contagiosum and followed up on 4, 8 and 12 weeks. Among 25 patients in group A, 72% (n=18) patients showed complete response, and in group Results: B, 64% (n=16) patients showed complete response, at the end of therapy. Maximum response in group A was around 8 weeks in 52% patients and in group B around 12 weeks in 56% patients. Both techniques of autoinoculation are simple, safe Conclusions: , efcacious and cost- effective treatment modalities with minimum recurrences and adverse effects.
Authors: Yogita Ashiya, Rajkumar Kothiwala, Tanvi Jain
Institution: Jawaharlal Nehru Medical College
Language: English
Subfield: Virology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W4404108745