Neurocutaneous Melanocytosis‐Associated Hydrocephalus: The Memorial Sloan Kettering Experience from 2001 to 2022
Year: 2024
Type: article
Study design: Case Report
Abstract: We report two neurocutaneous melanocytosis (NCM) patients who required ventriculoperitoneal shunt placement and subsequently developed intraperitoneal melanoma. These patients with NCM are at an increased risk for developing NRAS-associated melanomas in the central nervous system, which in turn may lead to symptomatic hydrocephalus requiring cerebrospinal fluid diversion. Due to the rarity of NCM, current knowledge on disease progression and appropriate management is limited. Ongoing studies aiming to better understand this condition and inform its clinical management may help to identify risk factors for developing more severe complications.
Source: Pediatric Blood & Cancer
DOI: 10.1002/pbc.31434
Authors: Scarlett Rodriguez, Francesca DeIeso‐Frechette, Chidobe Umeasor, Christianah Alli, Caline Azzi, Sofia Haque, John A Pugh, Nathan Meeker, Yasmin Khakoo
Language: English
Subfield: Cellular and Molecular Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: green
Funder: National Cancer Institute
OpenAlex ID: W4404114769