Work

Navigating the Diagnostic Challenges in Lymph Node Cytology: The Case of Reactive Hyperplasia

Year: 2024

Type: article

Abstract: Fine needle cytology (FNC) is a pivotal diagnostic tool for distinguishing between benign and malignant lymphadenopathies mainly because of its minimal invasiveness, cost-effectiveness and accuracy. A major requirement for maximising diagnostic accuracy is proper sample management of aspirated cellular material. In this diagnostic process, the morphological evaluation of adequate smears is paramount, guiding cytopathologists in the selection of appropriate ancillary tests through the recognition of cell size and patterns of distribution. Here, we describe a peculiar 'concentric ovals distribution pattern', frequently observed in the FNC of benign reactive lymph nodes, which may represent an aid in the cytological diagnosis of reactive hyperplasia.

Source: Cytopathology

DOI: 10.1111/cyt.13455

Authors: Elena Vigliar, Gennaro Acanfora, Mauro Buono, Claudio Bellevicine, Marco Picardi, Giancarlo Troncone

Institutions: University of Naples Federico II, Federico II University Hospital

Language: English

Topic: Lymphadenopathy Diagnosis and Analysis

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,710