Work

The Utility of IVIG in the Management of Autoimmune Encephalitis: A Retrospective Case Series

Year: 2024

Type: article

Abstract: Autoimmune encephalitis (AE) involves inflammation of the brain parenchyma due to autoantibodies targeting neuronal cell surfaces or synaptic proteins [1]. It is a rapidly progressive disorder and can lead to significant morbidity, prolonged hospital stays, and possible mortality. Intravenous immunoglobulin (IVIG) is a treatment for AE that may be used when other acute treatments are ineffective or contraindicated. It has been proven useful in many autoimmune disorders [2-5], though is underutilized in AE due to lack of controlled studies. We report a retrospective case series, in which the use of IVIG was a life-saving measure for two patients with autoimmune encephalitis. These cases demonstrate that IVIG may be an important treatment option to consider for both acute and maintenance management of AE.

Source: International Journal of Neurology and Neurotherapy

DOI: 10.23937/2378-3001/1410127

Authors: Frustaci Katherine, Qutab Natasha, Eckert Svetlana

Institution: University at Buffalo, State University of New York

Language: English

Topic: Autoimmune Neurological Disorders and Treatments

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4404120261

FWCI:

Cites:

Cited by:

Related to: 10