Work

Adult-Onset Eccrine Angiomatous Hamartoma Associated with Lower Extremity Venous Insufficiency: A Case Report

Year: 2024

Type: article

Abstract: Introduction: Eccrine angiomatous hamartoma (EAH) is a benign tumor characterized by the proliferation of eccrine glands and vascular structures. It can be congenital or appear during childhood, with rare cases arising in adults. EAH typically presents as a solitary purplish plaque or nodule but a multifocal presentation in a blaschkoid or segmental distribution has been described. Case Presentation: We report the case of an extensive EAH following the territory of the superficial veins of the lower limbs, arising in an adult diagnosed with venous insufficiency at a young age and that worsened after saphenectomy. Conclusion: The histopathological and ultrasonographic characteristics suggest that this case may represent a new instance of EAH associated with arteriovenous malformation. We hypothesize that there might be common molecular pathways linking both conditions and that, in predisposed patients, saphenectomy can exacerbate EAH.

Source: Skin Appendage Disorders

DOI: 10.1159/000541808

Authors: Isabela Dorado Caycedo, Juan C.H. López Takegami, Eduardo A. Rivera Perdomo, Claudia P. González Díaz

Institution: Fundación Universitaria Sanitas

Language: English

Topic: Cancer and Skin Lesions

Subfield: Dermatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4404124361