Work

Enhanced antifungal activity of siRNA-loaded anionic liposomes against the human pathogenic fungus Aspergillus fumigatus

Year: 2024

Type: article

Abstract: . Targeting mRNAs of three key genes, these liposomes visibly inhibited fungal growth, demonstrating for the first time the antifungal potential of siRNA against human fungal pathogens.

Source: Nanoscale

DOI: 10.1039/d4nr03225j

Authors: Yidong Yu, Theresa Vogel, Sina Hirsch, Jürgen Groll, Krystyna Albrecht, Andreas Beilhack

Institutions: University of Würzburg, Universitätsklinikum Würzburg, Teikyo University

Language: English

Topic: RNA Interference and Gene Delivery

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funders: Deutsche Forschungsgemeinschaft, Julius-Maximilians-Universität Würzburg, Bayerisches Staatsministerium für Wissenschaft und Kunst, Japan Society for the Promotion of Science, Graduate School of Life Sciences, Julius-Maximilians-Universität Würzburg

Awards: GRK 2157: 3D Gewebemodelle zur Untersuchung von mikrobiellen Infektionen durch Pathogene des Menschen, G2235679154, G4911582576, TRR 225: Von den Grundlagen der Biofabrikation zu funktionalen Gewebemodellen, G5470529961, G5551646253, TRR 124: Pathogene Pilze und ihr menschlicher Wirt: Netzwerke der Interaktion, G6983619631

OpenAlex ID: W4404143803

FWCI: 0.461

Cites: 42

Cited by: 4

Related to: 10