Barraquer–Simons syndrome: A rare case of acquired partial lipodystrophy after pregnancy with diabetes mellitus
Year: 2024
Type: article
Study design: Case Report
Abstract: Barraquer–Simons syndrome (BSS) is an uncommon acquired partial lipodystrophy (APL) characterized by gradual, progressive loss of subcutaneous fat limited to the upper part of the body. It is a rare condition of uncertain origin typically appearing in early adolescence with a higher incidence among females with autoimmunity and C3 hypocomplementemia. Approximately 250 cases were reported worldwide, we present a case of BSS that began after pregnancy. A biopsy of the affected areas reveals reduced adipocytes. Metabolic abnormalities are relatively uncommon in APL compared to other forms of lipodystrophy, affecting around 10% of patients. At present, there is no treatment available to stop the disease’s progression. Management options are limited to restoration through lipomodelling or fat grafting in the affected regions. This report focuses on a 58-year-old patient with BSS who started post-pregnancy, and who also has diabetes mellitus and low C3 levels.
Source: Cosmoderma
Authors: Anjali Gautam, Purnachandra Badabagni, Surender Singh, Archana Mavoori, Pranavi Katike, Sravya Himasri Bhamidipati
Language: English
Topic: Body Contouring and Surgery
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4404157546