Elevated metabolic score for visceral fat was associated with increased prevalence of gallstones in American adults: a cross-sectional study
Year: 2024
Type: article
Study design: Observational Study
Abstract: Background: Metabolic Visceral Fat Score (METS-VF) recently introduced is posited to be a superior metric for assessing visceral adipose tissues (VAT) compared to traditional obesity indexes. This study aims to elucidate the correlation between METS-VF and the incidence of gallstones. Methods: In this cross-sectional study, the data from the National Health and Nutrition Examination Survey (NHANES) during the period from 2013 to 2020 were analyzed. And the correlation between METS-VF and the incidence of gallstones was explored through multivariate logistic regression analysis, receiver operating characteristic (ROC) curve, subgroup analysis and restricted cubic spline (RCS) regression. Results: < 0.001). Logistic regression analyses indicated a significant positive correlation between METS-VF and the risk of gallstones (OR = 3.075, 95% CI: 2.158, 4.381). Subgroup analyses further revealed a stronger correlation between gallstones and METS-VF in subjects over 50 years old. RCS regression identified a non-linear positive correlation, with an inflection point at 6.698. Finally, the area under the ROC curve (AUC) of METS-VF was significantly larger (AUC = 0.705, 95%: 0.685, 0.725) than those of traditional obesity indexes and other VAT surrogate markers. Conclusion: This study is the first to reveal a significant positive correlation between the prevalence of gallstones and METS-VF, with METS-VF outperforming other VAT surrogate markers in the diagnosis of gallstones.
Source: Frontiers in Medicine
Authors: Hao Lin, Kexuan Shi, Shuang Luo, Wu Ye, Xiaoniao Cai
Institution: Wenzhou Medical University
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,295
OpenAlex ID: W4404159820