Work

Association between age and comorbid insomnia and sleep apnea

Year: 2024

Type: article

Abstract: PURPOSE: To investigate the age-related prevalence of comorbid insomnia and sleep apnea (COMISA). METHODS: A single-night polysomnography with video monitoring was conducted on 2176 Chinese adults (ages 18-102) to screen for obstructive sleep apnea (OSA). Insomnia was defined as difficulty initiating or maintaining sleep, or early morning awakening at least three times per week for more than three months, accompanied by daytime symptoms such as irritability, fatigue, or anxiety. RESULTS: Of the participants, 981 met the criteria for COMISA, defined by an apnea-hypopnea index (AHI) of ≥5 and the presence of insomnia. Compared to patients with OSA only (n = 433), COMISA patients were more often female (48 % vs. 24 %), had longer sleep onset latency (5.8 min), shorter total sleep time (14.0 min), lower AHI (14.4 points), and higher mean peripheral oxygen saturation (0.6 %; all p < 0.05). The prevalence of COMISA versus OSA only was 51.9 % vs. 48.1 % in participants under 50 years, compared to 78.1 % vs. 21.9 % in those aged 70 or older. Logistic regression analysis adjusted for sex showed a 3 % increase in the odds of COMISA (95 % CI: 1.02-1.04) with each additional year of age. CONCLUSIONS: Our findings reveal a significant association between increasing age and the development of COMISA, underscoring the need for heightened clinical awareness of this condition in elderly patients.

Source: Sleep Medicine

DOI: 10.1016/j.sleep.2024.11.011

Authors: Meina Wu, Pei Xue, Jinzhu Yan, Christian Benedict

Institutions: Fujian Provincial Hospital, Uppsala University, Fujian Medical University

Language: English

Topic: Obstructive Sleep Apnea Research

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,840