Work

The associations between exposure to ambient air pollution and coagulation markers and the potential effects of DNA methylation

Year: 2024

Type: article

Study design: Observational Study

Abstract: (6.95 μg/m³) was associated with 40.25 % (95 %CI: 14.83, 65.67) increase in plasminogen activator inhibitor-1 (PAI-1). Decreased methylation at CpG sites was associated with exposure to air pollution. However, DNA methylation did not mediate the association between ambient air pollution and coagulation. Our study revealed the harmful impact of ambient air pollution on coagulation function but found no significant mediation effects of DNA methylation.

Source: Journal of Hazardous Materials

DOI: 10.1016/j.jhazmat.2024.136433

Authors: Yan Chen, Guang-Hui Dong, Shuai Li, Yuewei Liu, Shanshan Li, Yuming Guo, Chongjian Wang, Gongbo Chen

Institutions: Sun Yat-sen University, The University of Melbourne, Monash University, Zhengzhou University

Language: English

Topic: Air Quality and Health Impacts

Subfield: Health, Toxicology and Mutagenesis

Field: Environmental Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,340

Funders: National Natural Science Foundation of China, Natural Science Foundation of Henan Province, National Health and Medical Research Council

Awards: New Knowledge and Research Capacity for Health Impacts of Global Environmental Change with Big Data, Novel Approach and New Technology, Health Risk Assessment of Bushfire Smoke on Children and Pregnancy Outcomes, G7319179190, G8943690793

OpenAlex ID: W4404171603

FWCI: 1.583

Cites: 61

Cited by: 10

Related to: 10