Work

Cover Feature: Synthesis and Thermodynamic Evaluation of Sialyl‐Tn MUC1 Glycopeptides Binding to Macrophage Galactose‐Type Lectin (ChemBioChem 18/2024)

Year: 2024

Type: article

Abstract: Isothermal titration calorimetry (ITC) analysis of the binding of hMGL to Tn and sialyl-Tn MUC1 glycopeptides revealed a dynamic process in which lectin molecules bind to carbohydrate ligands and jump from ligand to ligand along the glycopeptides’ backbone. More details can be found in article 10.1002/cbic.202400391 by Maré Cudic and co-workers.

Source: ChemBioChem

DOI: 10.1002/cbic.202481804

Authors: Ramya Ayyalasomayajula, Ivet Boneva, David Ormaza, Andrew Whyte, Kamran Farook, Zachary Gorlin, Evelyn Yancey, Sabine André, Herbert Kaltner, Maré Cudic

Institutions: Florida Atlantic University, Ludwig-Maximilians-Universität München

Language: English

Topic: Glycosylation and Glycoproteins Research

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

OpenAlex ID: W4404174908

FWCI:

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