Phosphine‐mediated one‐pot reactions: Syntheses of β ‐acylated alkylidene indandiones and furo[2,3‐ f ]dibenzotropones via MBH ‐type annulation/acylation or Wittig reaction
Year: 2024
Type: article
Abstract: Phosphine‐mediated one‐pot reactions have been developed that involve two mechanistically distinct reactions assembled in one reaction vessel via the sequential addition process. The first step involves MBH‐type annulation of α , β ‐ynones to afford cyclic products in each case, which then engages in subsequent β ‐acylation or intramolecular Wittig reactions. The reaction conditions are mild and efficient, providing acylated alkylidene indandiones in 70%–99% yields or furo[2,3‐ f ]dibenzotropones in 65%–91% yields, respectively.
Authors: Po‐Chung Chien, You‐Jie Chen, Gangababu Marri, Yi‐Ru Chen, Ching‐Fen Chang, Pei‐Shan Wu, Wenwei Lin
Institution: National Taiwan Normal University
Language: English
Topic: Catalytic Alkyne Reactions
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: bronze
Award: G4124501975
OpenAlex ID: W4404195475