Quality of life as a reflection of metabolic indicators in patients undergoing programmed hemodialysis
Year: 2024
Type: article
Study design: Observational Study
Abstract: Metabolic disorders associated with chronic kidney disease (CKD) can lead to a decrease in the quality of life of patients on hemodialysis. The aim of this study is to analyze the correlation between quality of life (QOL) in patients receiving treatment with PHD and clinical and laboratory indicators. Material and methods. 251 patients with stage 5 CKD were included in the study. There were 108 men and 143 women. The mean age was 54.4 ± 9.9 years. All participants completed a specific quality of life questionnaire KDQOL-SF. Results. The interviewed patients reported more concern about symptoms such as weakness, dizziness, and muscle pain (U = 765, p < 0.001), which was correlated with albumin levels (R = 0.5, p < 0.01) and calcium-phosphorus product levels (R = –0.48, p < 0.05). They also expressed concern about the inability to travel or follow a special diet (U = 553, p < 0.005), which correlated with heart rate levels (R = –0.51, P < 0.1) and serum potassium levels (R = –0.6, P < 0.1). Additionally, the burden of CKD correlated with triglycerides (R = 0.36, p = 0,01).Work capacity is associated with age (R = –0.54; p < 0.001), eKT/V (R = 0.47; p < 0.01). Indicators of cognitive function correlate with blood pressure (BP) (R = –0.51, p < 0,001) and pulse pressure (P = –0,55, p < 0,01). Sexual functions are associated with BP (R = –0,64, p < 0,05), calcium levels (R = 0,76, p > 0.80), iron (0,42, p = 0,90), transferrin saturation coefficient (0.5, p = 0.91). Sleep quality correlates with calcium-phosphate production (0.3, p > 0.15). The feeling of social support correlates with magnesium (0,3, P > 0,8), calcium (0.2, P > 0,1). Conclusions. Correlations between quality of life, blood pressure, albumin, and calcium phosphate metabolism, iron, were found.
Authors: E. N. Ievlev, I. A. Kazakova
Institution: Izhevsk State Medical Academy
Language: English
Subfield: Nephrology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4404199996