Work

Macropolycytes as a sepsis biomarker

Year: 2024

Type: article

Abstract: • Analyzers can erroneously count macropolycytes as monocytes. • When a high monocytes count is obtained by the analyzers, a peripheral blood film should be performed to confirm this assessment. • The identification of macropolycytes can play an important role as a sepsis biomarker. A 16-year-old male patient who underwent a kidney transplant developed a septic shock. A full blood count (FBC) was performed and the presence of monocytosis in the automatic FBC, the overlap between neutrophils and monocytes in the WBC scatter plot, and a “MO blast” flag triggered by the analyzer, led to a peripheral blood film (PBF). PBF revealed the presence of macropolycytes that were erroneously count as monocytes by the analyzer. Macropolycytes can play an important role as a sepsis biomarker.

Source: Morphologie

DOI: 10.1016/j.morpho.2024.100923

Author: M.P. Barros Pinto

Institutions: University of Lisbon, Centro Hospitalar Lisboa Norte, Hospital de Santa Maria

Language: English

Topic: Clinical Laboratory Practices and Quality Control

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,120