Work

Descripción de alteraciones histopatológicas en riñones de Rattus norvegicus seropositivos a Leptospira spp.

Year: 2024

Type: article

Abstract: The aim of this study was to describe the most common histopathological findings observed by Hematoxylin-Eosin staining in kidneys of Rattus norvegicus naturally infected and seropositive to Leptospira spp using the Microscopic Agglutination Test (MAT) technique. In total, 165 rodents were captured from three locations in Antioquia (Turbo and Medellín). Kidney samples were taken from the seropositive rodents by MAT and Hematoxylin-Eosin staining was used to evaluate the microscopic lesions and Warthin- Starry to visualize the bacteria. The most frequent morphological diagnoses were chronic interstitial nephritis (45.0%), followed by vascular congestion (20.1%) and chronic interstitial pyelonephritis (10.6%). The pathological processes were classified 73.1% as moderate and 26.9% as mild. The agent was not observed with the Warthin starry stain.

Source: Revista de Investigaciones Veterinarias del Perú

DOI: 10.15381/rivep.v35i4.25319

Authors: Ingrid L. Jaramillo Delgado, Diego A. Aranzazu Taborda, Santiago Duque-Arias

Institutions: Universidad CES, Universidad de Antioquia, Corporación Universitaria Remington

Language: English

Topic: Leptospirosis research and findings

Subfield: Parasitology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4404229484

FWCI:

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