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Neuroretinitis Associated With Covid-19 Infection and Varicella-zoster Virus Reactivation

Year: 2024

Type: article

Abstract: PURPOSE: To report a case of neuroretinitis as the presenting manifestation of COVID-19 infection alongside varicella-zoster virus reactivation, in the absence of other systemic symptoms. METHODS: A case report. RESULTS: A previously healthy 15-year-old boy presented with a 1-week history of acute unilateral visual loss and clinical findings consistent with neuroretinitis. Diagnostic work-up revealed a positive polymerase chain reaction test of nasopharyngeal swab for COVID-19 and serology showed the presence of immunoglobulin M and immunoglobulin G antibodies for varicella-zoster virus. After a comprehensive treatment regimen involving IV acyclovir, high-dose IV steroids, and oral doxycycline, rapid and remarkable improvements were observed. The macular star and optic disk swelling regressed, and visual acuity improved from 20/200 to 20/20. CONCLUSION: This case offers valuable insights into the neuroretinitis associated with COVID-19 infection and varicella-zoster virus reactivation.

Source: Retinal Cases & Brief Reports

DOI: 10.1097/icb.0000000000001694

Authors: Ana Uršula Gavrić, Evelien Margareta Mylemans, Nataša Vidovič Valentinčič

Institutions: University of Ljubljana, Ljubljana University Medical Centre, University of Antwerp

Language: English

Topic: Retinal and Optic Conditions

Subfield: Ophthalmology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4404230823

FWCI:

Cites: 10

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Related to: 10