Year: 2024
Type: article
Study design: Case Report
Abstract: Statin-induced immune-mediated necrotising myopathy (IMNM) is a rare complication associated with statin use. IMNM is classified as one of the inflammatory myopathies characterised by myalgia and elevated serum creatine kinase (CK) levels. In this case report, we present a 58-year-old woman who developed IMNM secondary to atorvastatin use. The patient presented with proximal myopathy and increased CK levels. Laboratory analysis revealed the presence of anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) autoantibodies, and a muscle biopsy confirmed the presence of myofibre necrosis.
Source: Ugeskrift for Læger
DOI: 10.61409/v01240030
Authors: Nerma Todorovac, Anne Bruun Krøigård, Alice Ashouri Christiansen, Ghassan Jadou
Institutions: Sygehus Sønderjylland, Odense University Hospital
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4404249349