Modifying the timing of breakfast improves postprandial glycaemia in people with type 2 diabetes: A randomised controlled trial
Year: 2024
Type: article
Study designs: Randomized Controlled Trial, Clinical Trial
Abstract: Investigate the effects of breakfast timing on postprandial glycaemia in adults with type 2 diabetes (T2D), and the impact of a 20-min walk after breakfast. Eleven adults with T2D (57 ± 7 y; HbA1c 7.4 ± 1%) participated in a six-week randomised crossover controlled trial comprising three 4-day conditions: Early (0700 h), Mid (0930 h) and Delayed (1200 h). After each condition, a second 4-day intervention of 20-min walk after each condition was undertaken. Standardised breakfast was provided. Interstitial glucose and physical activity were measured. Incremental area under the curve (iAUC) 2-h post-breakfast, 24-h iAUC, and fasting glucose were analysed with linear mixed-effects models. Cohen's d of the 2-h iAUC post-breakfast 20-min walk was calculated. Mid and Delayed had lower 2-h post-breakfast iAUC (p < 0.002, −57 mmol/L×2h; p < 0.02, −41 mmol/L×2h) compared to Early. There were no differences in fasting (0600 h) glucose or 24-h iAUC. There was a small effect of the 20-min walk on lowering 2-h post-breakfast iAUC for Early (d = 0.35) and Delayed (d = 0.37), with no effect in Mid. In people with T2D, delaying breakfast from 0700 h to mid-morning or midday reduced postprandial glycaemia. Additional post-meal walking for 20 min had a small effect in lowering postprandial glycaemia when breakfast was at 0700 h or midday, but provided no additional benefit when breakfast was at mid-morning. • Delaying breakfast from 0700 h to 0930 h or 1200 h reduces postprandial glycaemia. • A 20-min walk post-breakfast reduces postprandial hyperglycaemia in Early (0700 h) and Delayed (1200 h) conditions. • Delaying breakfast to 0930 or 1200 h is a low-cost strategy to improve glycaemic management in people with type 2 diabetes.
Institution: Australian Catholic University
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $3,890
Funder: Australian Catholic University
OpenAlex ID: W4404258936