The importance of combined Candida & Borrelia biofilms in Lyme’s disease and the value of ultrasound treatment: A medical hypothesis
Year: 2024
Type: article
Abstract: • Mechanisms of bacteria’s persistence into the human host may involve Borrelia ’s ability to interact with Candida. • Candidiasis can product mycotoxins and resemble to Lyme’s disease. • Ultrasound could destroy biofilms. The chronic form of Lyme’s disease is gaining general recognition by the CDC in Atlanta. The factors contributing to the chronicity of this disease are well-documented in the current literature. Biofilms are known being key-factors for the persistence of many infections and thus may explain the passage to further disease’s chronicity. Other mechanisms of bacteria’s persistence into the human host may involve the ecosystem and the Borrelia ’s ability to interact with the surrounding microorganisms, like Candida. Moreover, candidiasis could be at the origin of clinical syndromes resembling Lyme’s disease, via the production of mycotoxins. In addition to antibiotic therapy, we hypothesize that the treatment of chronic Lyme’s disease could include the administration of antifungal drugs. It also seems important to evaluate the drugs that could destroy biofilms. An unconventional and original approach could be to add to the conventional therapy mechanical tools to destroying these biofilms by using low-frequency ultrasound.
Source: Medical Hypotheses
Authors: Jean-Pierre Tournier, Pierre-Yves Marcy, Christian Perronne, Alexis Lacout
Language: English
Subfield: Parasitology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: hybrid
Estimated APC paid: $2,820
OpenAlex ID: W4404297316