“Silent” HPV-associated cervical cancer – isolated cerebellar metastasis as unusual sign of cervical adenocarcinoma: a case report and literature review
Year: 2024
Type: article
Abstract: Background.This report focuses on an unusual case of primary central nervous system metastasis (CNS) from gynaecological cancer, specifically endocervical carcinoma, which typically occurs as part of a disseminated disease.Brain metastases from cervical cancer are rare, occurring in only 2% of cases.We reported data from hospital registry and the available literature with using the PRISMA methodology. Case presentation.The patient, a 48-year-old woman without relevant medical history or gynaecological symptoms, went to the Emergency Room with progressive neurological symptoms.Imaging revealed obstructive hydrocephalus due to a mass in the IV ventricle, later identified as a cerebellar metastasis.Despite negative routine cervical screening, subsequent examinations revealed advanced cervical cancer with aggressive histology.The patient's poor performance status precluded standard treatments, so she underwent palliative care.Unfortunately, she succumbed to the disease after eight months.
Authors: M. Cerbone, A. Aquilino, M. Bardi, M. Mele, A. Galante, M. Bentivoglio, M. Dellino, A. Vimercati, G. Cormio, E. Cicinelli, M. Marinaccio
Institutions: University of Bari Aldo Moro, Istituto Tumori Bari
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4404304467