Work

Customized immunotherapy in OSCC: Leveraging neoantigens for precision medicine

Year: 2024

Type: article

Abstract: • Neoantigens enhance targeted immunotherapy in oral squamous cell carcinoma. • Personalized cancer vaccines activate T cells against tumor-specific antigens. • Adoptive T cell therapy utilizes patient's T cells for targeted cancer attack. • Combining neoantigens with checkpoint inhibitors boosts immune response. • Overcoming challenges will improve the feasibility of neoantigen therapies.

Source: Oral Oncology Reports

DOI: 10.1016/j.oor.2024.100687

Authors: Nitya Krishnasamy, Vikram S. Amberkar, Kochli Channapa Niranjan

Institutions: Saveetha University, Shri Dharmasthala Manjunatheshwara University

Language: English

Topic: Cancer Immunotherapy and Biomarkers

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,100